Anti-RNF34 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-RNF34 Polyclonal Antibody
中文名称： 锌指蛋白34抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IF ; WB
稀释比例： WB 1:500-2000. IF 1:50-200.

抗体信息

靶标： RNF34
别名： Caspase regulator CARP1, CARP 1, CARP-1, CARP1, Caspase regulator CARP1, Caspases-8 and -10-associated RING finger protein 1, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein Momo, hRFI, Human RING finger homologous to inhibitor of apoptosis protein, RFI, RIF, RIFF, RING finger protein 34, RING finger protein RIFF, RNF34, RNF34_HUMAN
背景说明： The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.
Swiss Prot： Q969K3
Gene ID： 80196
亚细胞定位： Cell membrane Cytoplasm Endomembrane system Nucleus Nucleus speckle Peripheral membrane protein cytosol
免疫原： Recombinant protein of human RNF34
Public Immunogen Range： 1-220aa
理论分子量： 42kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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