Anti-SART1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SART1 Polyclonal Antibody
中文名称： T淋巴细胞识别的鳞状细胞癌抗原抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IP ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200. IP 0.5μg-4μg.

抗体信息

靶标： SART1
别名： Ara1;HOMS1;SART1259;SNRNP110;Snu66
背景说明： This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Swiss Prot： O43290
Gene ID： 9092
亚细胞定位： Nucleus
免疫原： Recombinant protein of human SART1
Public Immunogen Range： 1-255aa
理论分子量： 90kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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