Anti-FGD4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-FGD4 Polyclonal Antibody
中文名称： FGD4蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： WB
稀释比例： WB 1:500-2000. IHC 1:50-200.

抗体信息

靶标： FGD4
别名： 9030023J02Rik, 9330209B17Rik, Actin filament binding protein frabin, Actin filament-binding protein frabin, CMT4H, DKFZp313E1818, DKFZp434K1572, FGD1 related F actin binding protein, FGD1-related F-actin-binding protein, Fgd4, FGD4_HUMAN, FLJ34370, FLJ42663, FRABP, FYVE, FYVE, RhoGEF and PH domain containing 4, MGC57222, RhoGEF and PH domain-containing protein 4, ZFYVE6, Zinc finger FYVE domain containing protein 6, Zinc finger FYVE domain-containing protein 6
背景说明： This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q96M96
Gene ID： 121512
亚细胞定位： Cell projection Cytoplasm cytoskeleton filopodium
免疫原： Recombinant protein of human FGD4
Public Immunogen Range： 99-198aa
理论分子量： 87kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。