Anti-RGS14 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-RGS14 Polyclonal Antibody
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200

抗体信息

靶标： RGS14
别名： Highly similar to rap1/rap2 interacting protein,
背景说明： This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Swiss Prot： O43566
Gene ID： 10636
亚细胞定位： Cell junction Cell membrane Cell projection Cytoplasm Membrane Nucleus PML body centrosome cytoskeleton dendrite dendritic spine microtubule organizing center postsynaptic cell membrane postsynaptic density spindle spindle pole synapse
免疫原： Recombinant protein of human RGS14
Public Immunogen Range： 230-510aa
理论分子量： 61kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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