Anti-CGAS Polyclonal Antibody,BR
Anti-CGAS Polyclonal Antibody
(订货以英文名为准)
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宿主:Rabbit
别名:C6orf150;cGAS;MB21D1
稀释比例:WB 1:500-2000. IHC 1:50-100.
蛋白分子量:50/59kDa
Gene ID:115004
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:A synthetic peptide of human MB21D1
亚细胞定位:Cell membrane Cytoplasm Membrane Nucleus
Swiss Prot:Q8N884
背景资料:Nucleotidyltransferase that catalyzes formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and exhibits antiviral activity. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of DNA in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to and activates TMEM173/STING, thereby triggering type-I interferon production.
克隆类型:Polyclonal Antibody
规格:50ul, 100ul, 注意：
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