Anti-ABL1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ABL1 Polyclonal Antibody
中文名称： 非受体酪氨酸激酶c-Abl抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC
稀释比例： IHC 1:25-100.

抗体信息

靶标： ABL1
别名： Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine protein kinase 1,Abl 1,ABL,ABL proto oncogene 1 non receptor tyrosine kinase,ABL1,ABL1_HUMAN,bcr/abl,bcr/c abl oncogene protein,c ABL,c abl oncogene 1 non receptor tyrosine kinase,c abl oncogene 1 receptor tyrosine kinase,c ABL1,JTK7,p150,Proto oncogene tyrosine protein kinase ABL1,Proto-oncogene c-Abl
背景说明： The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
Swiss Prot： P00519
Gene ID： 25
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human ABL1
理论分子量： 123kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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