Anti-KDM3B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-KDM3B Polyclonal Antibody
中文名称： 组蛋白去甲基转移酶JMJD1B抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:20-200.

抗体信息

靶标： KDM3B
别名： 5qNCA;NET22;C5orf7;JMJD1B
背景说明： JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
Swiss Prot： Q7LBC6
Gene ID： 51780
亚细胞定位： Nucleus
免疫原： Recombinant protein of human KDM3B
理论分子量： 192kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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