Anti-PRMT5 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PRMT5 Polyclonal Antibody
中文名称： 组蛋白精氨酸甲基转移酶5抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： PRMT5
别名： JBP1;SKB1;IBP72;SKB1Hs;HRMT1L5
背景说明： Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation.
Swiss Prot： O14744
Gene ID： 10419
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human PRMT5
理论分子量： 54/68/71/73kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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