Anti-GRM4 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GRM4 Polyclonal Antibody
中文名称： 代谢型谷氨酸受体4抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human ; Rat ; Mouse
应用： IHC-P
稀释比例： IHC-P 1:25-100.

抗体信息

靶标： GRM4
别名： G protein coupled receptor family C group 1 member D, G protein coupled receptor GRM 4, G protein coupled receptor GRM4, Glutamate receptor metabotropic 4, GPRC 1D, GPRC1D, GRM 4, GRM4, GRM4_HUMAN, Metabotropic glutamate receptor 4, mGlu 4, mGlu R4, mGlu4, mGluR 4, mGluR4
背景说明： L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q14833
Gene ID： 2914
亚细胞定位： Membrane
研究领域： 免疫学 ; 细胞生物学 ; 信号传导
免疫原： A synthetic peptide of human GRM4
理论分子量： 102/87/84kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。