Anti-WISP2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-WISP2 Polyclonal Antibody
中文名称： WNT1诱导信号通路蛋白2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:30-150.

抗体信息

靶标： WISP2
别名： CTGFL, CCN family member 5, CCN5, Connective tissue growth factor like protein, Connective tissue growth factor related protein 58, Connective tissue growth factor-like protein, Connective tissue growth factor-related protein 58, CT58, CTGF L, CTGFL, CTGF-L, WISP 2, WISP-2, Wisp2, WISP2_HUMAN, WNT1 inducible signaling pathway protein 2, WNT1-inducible-signaling pathway protein 2
背景说明： This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Swiss Prot： O76076
Gene ID： 8839
亚细胞定位： Secreted
免疫原： A synthetic peptide of human WISP2
理论分子量： 27/23kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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