Anti-CHAMP1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CHAMP1 Polyclonal Antibody
中文名称： 锌指蛋白828抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC ; WB
稀释比例： WB 1:200-1000. IHC 1:25-100.

抗体信息

靶标： CHAMP1
别名： CAMP;CHAMP;MRD40;ZNF828;C13orf8
背景说明： CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
Swiss Prot： Q96JM3
Gene ID： 283489
亚细胞定位： Nucleus Cytoplasm
免疫原： A synthetic peptide of human CHAMP1
理论分子量： 89kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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