Anti-ACVR2B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ACVR2B Polyclonal Antibody
中文名称： 激活素受体2B抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC ; WB
稀释比例： WB 1:200-1000. IHC 1:50-200.

抗体信息

靶标： ACVR2B
别名： Activin Receptor Type IIB, ACTR-IIB, Activin A receptor type IIB, Activin receptor type 2B, Activin receptor type IIB, Activin receptor type-2B, ActR IIB, ACTR-IIB, ActRIIB, ACVR 2B, ACVR2B, AVR2B_HUMAN, HTX4, MGC116908
背景说明： Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Swiss Prot： Q13705
Gene ID： 93
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human ACVR2B
理论分子量： 58kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。