Anti-ADAM10 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ADAM10 Polyclonal Antibody
中文名称： 去整合素样金属蛋白酶10抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:25-100

抗体信息

靶标： ADAM10
别名： AD10;AD18;CD156c;CDw156;HsT18717;MADM;RAK;kuz
背景说明： Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).
Swiss Prot： O14672
Gene ID： 102
亚细胞定位： Cytoplasm Cell membrane Endomembrane system Single-pass type I membrane protein
免疫原： Recombinant protein of human ADAM10
理论分子量： 84kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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