Anti-VWA5A Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-VWA5A Polyclonal Antibody
中文名称： 包含von Willebrand因子A结构域蛋白5A抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-150.

抗体信息

靶标： VWA5A
别名： Breast cancer suppressor candidate 1, LOH11CR2A, LHR2A, LOH11CR2A, BCSC 1, BCSC-1, BCSC1, Breast cancer suppressor candidate-1, Loss of heterozygosity 11 chromosomal region 2 gene A, Loss of heterozygosity 11 chromosomal region 2 gene A protein, Ortholog of mouse AW551984, VMA5A_HUMAN, von Willebrand factor A domain containing 5A, von Willebrand factor A domain-containing protein 5A, Vwa5a
背景说明： VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.
Swiss Prot： O00534
Gene ID： 4013
亚细胞定位： Cytoplasm
免疫原： Recombinant protein of human VWA5A
理论分子量： 86kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。