Anti-PFKFB3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PFKFB3 Polyclonal Antibody
中文名称： 6-磷酸果糖-2-激酶/果糖-2, 6-二磷酸酶3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human ; Rat
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： PFKFB3
别名： 6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase, 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3, 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme, 6PF 2-K/Fru 2,6 P2ase 3, fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase, Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase, iPFK 2, IPFK2, PFK/FBPase 3, PFK-2, PFK2, Renal carcinoma antigen NY REN 56, uPFK 2, PFKFB3, F263_HUMAN
背景说明： The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Swiss Prot： Q16875
Gene ID： 5209
亚细胞定位： Cytosol Nucleus
研究领域： 新陈代谢 ; 细胞生物学
免疫原： A synthetic peptide of human PFKFB3
理论分子量： 60kDa

其它标识

纯化方法： Affinity purification
储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

产品介绍 Product Introduction

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注意事项 Considerations

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