Anti-PINK1 Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PINK1 Monoclonal Antibody
中文名称： 肿瘤相关胰蛋白酶抑制剂1抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG克隆号 5C6预测
交叉反应：： Human;Mouse
应用： IF ; ICC ; IHC ; WB
稀释比例： WB 1:200-1000. IHC 1:50-100. ICC 1:25. IF 1:25.

抗体信息

靶标： PINK1
别名： PINK1_HUMAN, PTEN Induced Putative Kinase 1, PTEN-Induced Putative Kinase Protein 1, BRPK, Serine/Threonine-Protein Kinase PINK1, Mitochondrial, Parkinson Disease (Autosomal Recessive) 6, Protein Kinase BRPK, EC 2.7.11.1, PARK6
背景说明： Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN . Targets PRKN to dysfunctional depolarized mitochondria through the phosphorylation of MFN2 . Activates PRKN in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PRKN and (2) mediating phosphorylation of ubiquitin, converting PRKN to its fully-active form . Required for ubiquinone reduction by mitochondrial complex I by mediating phosphorylation of complex I subunit NDUFA10 (By similarity).
Swiss Prot： Q9BXM7
Gene ID： 65018
亚细胞定位： Cytoplasm Mitochondrion
免疫原： Recombinant protein of human PINK1
理论分子量： 63kDa

其它标识

纯化方法： Affinity purification
储存液： 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。