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- Anti-JNK1+JNK2+JNK3 Polyclonal Antibody,BR
Anti-JNK1+JNK2+JNK3 Polyclonal Antibody,BR
Anti-JNK1+JNK2+JNK3 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-JNK1+JNK2+JNK3 Polyclonal Antibody中文名称: 氨基末端激酶1/2/3 抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Rat ; Mouse ; Human预测
交叉反应:: Dog;Pig;Cow
应用: ELISA ; FCM ; IF ; IHC ; WB
稀释比例: WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1ug/Test. IF 1:100-500.
抗体信息
靶标: JNK1+JNK2+JNK3别名: c Jun N terminal kinase 2;c Jun N terminal kinase 3;JNK;JNK1;JNK2;JNK2ALPHA;JNK2BETA;JNK3;MAPK8;MAPK9
背景说明: JNK1(MAPK8) is a member of the MAP kinase family. JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7.JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.JNK3 is a neuron-specific form of c-Jun N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis.The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity.
Swiss Prot: P45983/P45984/P53779
Gene ID: 5599/5601/5602
亚细胞定位: Nucleus Cytoplasm
免疫原: A synthetic peptide of human JNK1+JNK2+JNK3
Public Immunogen Range: 151-250/384aa
理论分子量: 42-47kDa
其它标识
纯化方法: Affinity purification储存液: 0.01M TBS(pH7.4) with 1% BSA,0.03% Proclin300 and 50% Glycerol.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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