Anti-FOS Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-FOS Polyclonal Antibody
中文名称： c-fos抗体
规格： 100ul ; 50ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Rat ; Human ; Mouse预测
交叉反应： Cow(100%);Pig(93.3%);Sheep(86.7%);Cat(100%);Hamster(93.8%)
应用： IHC-P
稀释比例： IHC-P 1:50-200.

抗体信息

靶标： FOS
别名： Cellular oncogene fos, FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus, FOS, FOS protein, G0 G1 switch regulatory protein 7, G0S7, Oncogene FOS, Proto oncogene protein c fos, v fos FBJ murine osteosarcoma viral oncogene homolog, AP-1, p55, FOS_HUMAN, Proto-oncogene c-Fos, G0/G1 switch regulatory protein 7
背景说明： Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
Swiss Prot： P01100
Gene ID： 2353
亚细胞定位： Cytoplasm Endoplasmic reticulum Nucleus cytosol
研究领域： 肿瘤&癌症 ; 免疫学 ; 信号传导 ; 表观遗传
免疫原： A synthetic peptide of human FOS 种属同源性预测Public Immunogen Range 255-305/380aa
理论分子量： 41/29/36kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输 种属同源性预测

产品介绍 Product Introduction

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