Anti-USP8 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-USP8 Polyclonal Antibody
中文名称： 泛素特异性肽酶8抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human
应用： WB ; IHC
稀释比例： WB 1:5000-8000. IHC 1:50-200.

抗体信息

靶标： USP8
别名： HumORF8;SPG59;UBPY;KIAA0055;hUBPy;Ubiquitin thioesterase 8
背景说明： Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability.
Swiss Prot： P40818
Gene ID： 9101
亚细胞定位： Cell membrane Cytoplasm Endosome membrane Nucleus Peripheral membrane protein
免疫原： A synthetic peptide of human USP8
Public Immunogen Range： 220-270/1118aa
理论分子量： 128/115kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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