Anti-OGG1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-OGG1 Polyclonal Antibody
中文名称： 8-氧代鸟嘌呤DNA糖基化酶抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:25-100.

抗体信息

靶标： OGG1
别名： HMMH; HOGG1; MUTM; OGH1; N-glycosylase/DNA lyase
背景说明： DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Swiss Prot： O15527
Gene ID： 4968
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of human OGG1
Public Immunogen Range： 1-345aa
理论分子量： 22/36/39/40/46/47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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