Anti-PCSK5 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PCSK5 Polyclonal Antibody
中文名称： 前蛋白转化酶枯草杆菌蛋白酶/ kexin 型蛋白5抗体
规格： 50ul ; 100ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human ; Mouse ; Rat
应用： IHC-P
稀释比例： IHC-P 1:50-200.

抗体信息

靶标： PCSK5
别名： hPC6； PC5； PC6； PC6A； PCSK5； Proprotein convertase 5； Proprotein convertase 6； SPC6
背景说明： This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B).
Swiss Prot： Q92824
Gene ID： 5125
亚细胞定位： Cytoplasm
研究领域： 细胞生物学 ; 表观遗传
免疫原： Recombinant protein of human PCSK5Public Immunogen Range 564-913aa
理论分子量： 101/207kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

产品介绍 Product Introduction

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注意事项 Considerations

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