Anti-SPIN2B Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SPIN2B Polyclonal Antibody
中文名称： spindlin家族成员2B抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： SPIN2B
别名： SPIN2B;SPIN-2;SPIN-2B;SPIN2_duplicate;TDRD26;dJ323P24.2;spindlin-2B
背景说明： Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.
Swiss Prot： Q9BPZ2
Gene ID： 474343
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of human SPIN2B
Public Immunogen Range： 1-259aa
理论分子量： 29kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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