Anti-CCDC134 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CCDC134 Polyclonal Antibody
中文名称： 含Coiled-coil 结构域蛋白134抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： CCDC134
别名： CC134_HUMAN, ccdc134, coiled-coil domain containing 134, Coiled-coil domain-containing protein 134, dJ821D11.3, FLJ22349, MGC21013
背景说明： In extracellular secreted form, promotes proliferation and activation of CD8+ T cells, suggesting a cytokine-like function (PubMed:25125657). Enhances cytotoxic anti-tumor activity of CD8+ T cells (PubMed:25125657). May inhibit ERK and JNK signaling activity (PubMed:18087676, PubMed:23070808). May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling (PubMed:23070808). In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.
Swiss Prot： Q9H6E4
Gene ID： 79879
亚细胞定位： Nucleus Cytoplasm Secreted
免疫原： Recombinant protein of human CCDC134
Public Immunogen Range： 1-229aa
理论分子量： 27kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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