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Anti-ER81 Polyclonal Antibody,BR
Anti-ER81 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-ER81 Polyclonal Antibody中文名称: ets变体1抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human ; Mouse
应用: WB
稀释比例: WB 1:1000-3000.
抗体信息
靶标: ER81别名: DKFZp781L0674, ER81, ER81 protein, ETS translocation variant 1, ets variant gene 1, Ets-related protein 81, Etsrp81, ETV 1, ETV1, ETV1_HUMAN, MGC104699, MGC120533, MGC120534
背景说明: This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Swiss Prot: P50549
Gene ID: 2115
亚细胞定位: Nucleus
免疫原: A synthetic peptide of human ER81
Public Immunogen Range: 305-355/477aa
理论分子量: 43/48/50/53/55kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。