Anti-GLRX2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GLRX2 Polyclonal Antibody
中文名称： 谷氧还蛋白2抗体
规格： 50ul ; 100ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human预测
交叉反应： Chimpanzee(100%)
应用： IHC-P
稀释比例： IHC-P 1:50-200.

抗体信息

靶标： GLRX2
别名： bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2), bA101E13.1, CGI133, Glrx2, GLRX2_HUMAN, Glutaredoxin-2, Glutaredoxin-2, mitochondrial, GRX2, mitochondrial
背景说明： Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Swiss Prot： Q9NS18
Gene ID： 51022
亚细胞定位： Nucleus
研究领域： 新陈代谢 ; 细胞生物学 ; 信号传导 ; 表观遗传
免疫原： A synthetic peptide of human GLRX2 种属同源性预测Public Immunogen Range 114-164/164aa
理论分子量： 18/19kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输 种属同源性预测

产品介绍 Product Introduction

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注意事项 Considerations

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