Anti-GLRX2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GLRX2 Polyclonal Antibody
中文名称： 谷氧还蛋白2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： GLRX2
别名： bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2), bA101E13.1, CGI133, Glrx2, GLRX2_HUMAN, Glutaredoxin-2, Glutaredoxin-2, mitochondrial, GRX2, mitochondrial
背景说明： Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Swiss Prot： Q9NS18
Gene ID： 51022
亚细胞定位： Nucleus
免疫原： A synthetic peptide of human GLRX2
Public Immunogen Range： 114-164/164aa
理论分子量： 18/19kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。