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Anti-HEXB Polyclonal Antibody,BR
Anti-HEXB Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-HEXB Polyclonal Antibody中文名称: 己糖胺酶B, β多肽抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human
应用: WB
稀释比例: WB 1:1000-3000.
抗体信息
靶标: HEXB别名: ENC-1AS,HEL-248,HEL-S-111,Beta hexosaminidase beta chain, Beta hexosaminidase subunit beta, Beta N acetylhexosaminidase, Beta-hexosaminidase subunit beta chain A, Beta-N-acetylhexosaminidase subunit beta, Cervical cancer proto oncogene 7 protein, Cervical cancer proto-oncogene 7 protein, ENC 1AS, Epididymis luminal protein 248, HCC 7, HCC-7, HCC7, HEL 248, HEX B, Hexb, HEXB_HUMAN, Hexosaminidase B (beta polypeptide), Hexosaminidase B, Hexosaminidase subunit B, HexosaminidaseB, N acetyl beta glucosaminidase, N-acetyl-beta-glucosaminidase subunit beta
背景说明: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot: P07686
Gene ID: 3074
亚细胞定位: Cytoplasm
免疫原: A synthetic peptide of human HEXB
Public Immunogen Range: 80-130/556aa
理论分子量: 63kDa
其它标识
纯化方法: Octanoic acid-ammonium sulfate precipitation储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。