- 首页
- Anti-RFTN1 Polyclonal Antibody,BR
Anti-RFTN1 Polyclonal Antibody,BR
Anti-RFTN1 Polyclonal Antibody
(订货以英文名为准)猜你喜欢
CAS No:856562-93-1
CAS No:238754-67-1
CAS No:18297-63-7
CAS No:41748-71-4
CAS No:61076-89-9
CAS No:6919-61-5
产品属性 Product Attributes
基本信息
英文名称: Anti-RFTN1 Polyclonal Antibody规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: WB
稀释比例: WB 1:1000-3000.
抗体信息
靶标: RFTN1别名: MIG2;PIB10;PIG9;RAFTLIN;raftlin
背景说明: Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).
Swiss Prot: Q14699
Gene ID: 23180
亚细胞定位: Cell membrane Cytoplasm
免疫原: A synthetic peptide of human RFTN1
Public Immunogen Range: 65-115/578aa
理论分子量: 63kDa
其它标识
纯化方法: Octanoic acid-ammonium sulfate precipitation储存液: PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。