Anti-SUV39H2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SUV39H2 Polyclonal Antibody
中文名称： 杂色抑制因子3-9同系物2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： SUV39H2
别名： FLJ23414, H3 K9 HMTase 2, H3-K9-HMTase 2, Histone H3 K9 methyltransferase 2, Histone H3-K9 methyltransferase 2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone lysine N methyltransferase SUV39H2, Histone-lysine N-methyltransferase SUV39H2, KMT1B, Lysine N methyltransferase 1B, Lysine N-methyltransferase 1B, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Su(var)3 9 Drosophila homolog of 2, Su(var)3 9 homolog 2, Su(var)3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Suppressor of variegation 3-9 homolog 2, Suv39h2, SUV92_HUMAN
背景说明： Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation.
Swiss Prot： Q9H5I1
Gene ID： 79723
亚细胞定位： Nucleus Cytoplasm
免疫原： Recombinant protein of Human SUV39H2
Public Immunogen Range： 1-350aa
理论分子量： 26/40/46kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。