Anti-IDH1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-IDH1 Polyclonal Antibody
中文名称： 可溶性异柠檬酸脱氢酶1（NADP+）抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse预测
交叉反应：： Cow;Chimpanzee;Vole;Sheep
应用： IHC
稀释比例： IHC 1:50-200.

抗体信息

靶标： IDH1
别名： IDH1;HEL-216;HEL-S-26;IDCD;IDH;IDP;IDPC;PICD
背景说明： Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Swiss Prot： O75874
Gene ID： 3417
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of human IDH1
Public Immunogen Range： 350-400/414aa
理论分子量： 47kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。