Anti-EIF3G Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-EIF3G Polyclonal Antibody
中文名称： 真核起始因子3亚基G抗体
规格： 50ul ; 100ul ; 20ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Human ; Rat ; Mouse预测
交叉反应： Cow(100%);Zebrafish(100%);Xenopus laevis(92.9%);Xenopus tropicalis(85.7%)
应用： IHC-P
稀释比例： IHC-P 1:100-300.

抗体信息

靶标： EIF3G
别名： EIF3-P42;EIF3S4;eIF3-delta;eIF3-p44
背景说明： RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex， which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1， eIF-1A， eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation， including cell cycling， differentiation and apoptosis， and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
Swiss Prot： O75821
Gene ID： 8666
亚细胞定位： Cytoplasm
研究领域： 表观遗传 ; 心血管
免疫原： A synthetic peptide of human EIF3G 种属同源性预测Public Immunogen Range 1-51/320aa
理论分子量： 36kDa

其它标识

纯化方法： Octanoic acid-ammonium sulfate precipitation
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输 种属同源性预测

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。