Anti-ERCC6L Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ERCC6L Polyclonal Antibody
中文名称： DNA切除修复蛋白ERCC-6 样蛋白抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB ; IHC
稀释比例： WB 1:1000-3000. IHC 1:100-300.

抗体信息

靶标： ERCC6L
别名： ATP dependent helicase ERCC6 like, DNA excision repair protein ERCC 6 like, ERCC 6L, ERCC6L, Excision repair cross complementing rodent repair deficiency complementation group 6 like, Excision repair protein ERCC6 like, FLJ20105, MGC131695, PICH, Plk1 interacting checkpoint helicase, SNF2/RAD54 family protein, Tumor antigen BJ HCC 15, ERC6L_HUMAN
背景说明： DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin (PubMed:17218258). Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase (PubMed:17218258, PubMed:23973328). Functions as ATP-dependent DNA translocase (PubMed:23973328, PubMed:28977671). Can promote Holliday junction branch migration (in vitro) (PubMed:23973328).
Swiss Prot： Q2NKX8
Gene ID： 54821
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human ERCC6L
Public Immunogen Range： 832-1250aa
理论分子量： 141kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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