Anti-PAK2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PAK2 Polyclonal Antibody
中文名称： 丝氨酸/苏氨酸-蛋白激酶抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human ; Rat预测
交叉反应：： Rabbit
应用： WB
稀释比例： WB 1:1000-3000.

抗体信息

靶标： PAK2
别名： PAKalpha;p65-PAK;p21-activated kinase 1;S6/H4 kinase;p21-activated kinase 2;p58;PAK-2p27;p27;PAK-2p34;p34;C-t-PAK2;PAK65;PAKgamma;ARA; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; bPAK; beta-PAK;Oligophrenin-3;p21-activated kinase 3;
背景说明： This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene./The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell./The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.
Swiss Prot： Q13177
Gene ID： 5062
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human PAK2
Public Immunogen Range： 140-190/524aa
理论分子量： 58/61/62/63/65kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。