Recombinant Human SUMO1/Small ubiquitin-related modifier 1,BR

产品属性 Product Attributes

基本信息

别名： Small Ubiquitin-Related Modifier 1;SUMO-1;GAP-Modifying Protein 1;GMP1;SMT3 Homolog 3;Sentrin;Ubiquitin-Homology Domain Protein PIC1;Ubiquitin-Like Protein SMT3C;Smt3C;Ubiquitin-Like Protein UBL1;SUMO1;SMT3C;SMT3H3;UBL1
中文名称: Recombinant Human SUMO1/Small ubiquitin-related modifier 1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.5 .
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily.It is a family of small，related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation.SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system.This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport，DNA replication and repair，mitosis and signal transduction.SUMO1 is involved in a variety of cellular processes，such as nuclear transport，transcriptional regulation，apoptosis，and protein stability.SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off.Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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注意事项 Considerations

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