Recombinant Mouse B7-2/CD86/T-lymphocyte Activation Antigen CD86,BR

产品属性 Product Attributes

基本信息

别名： T-lymphocyte activation antigen CD86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;CD86
中文名称: Recombinant Mouse B7-2/CD86/T-lymphocyte Activation Antigen CD86
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family.B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance.Mouse CD86 shares 59% and 81% aa sequence identity with human and rat CD86，respectively.It contains 1 Ig-like C2-type domainand 1 Ig-like V-type domain.It is highly expressed on activated antigen presenting cells.CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production，by binding CD28 or CTLA-4.It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells，such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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