Recombinant Human FGF-1/FGFa/FGF acidic,BR

产品属性 Product Attributes

基本信息

别名： Fibroblast Growth Factor 1;FGF-1;Acidic Fibroblast Growth Factor;aFGF;Endothelial Cell Growth Factor;ECGFHeparin-Binding Growth Factor 1;HBGF-1;FGF1;FGFA
中文名称: Recombinant Human FGF-1/FGFa/FGF acidic
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM MOPS, 100mM Na2SO4, 1mM EDTA, pH 7.9.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： FGF acidic，also known as ECGF，FGF-1and HBGF-1，is a non-glycosylated heparin binding growth factor that is expressed in the brain，kidney，retina，smooth muscle cells，bone matrix，osteoblasts，astrocytes and endothelial cells.It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal，ectodermal，and endodermal origin.Its association with heparan sulfate is a prerequisite for activation of FGF receptors.Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta，exported to the cytosol，dephosphorylated，and degraded.Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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