Recombinant Human Pyruvate kinase PKM/PKM2,BR

产品属性 Product Attributes

基本信息

别名： Pyruvate kinase PKM;CTHBP;OIP-3;THBP1
中文名称: Recombinant Human Pyruvate kinase PKM/PKM2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris- HCl, 50mM NaCl, 0.05% Brij-35, 1mM DTT, pH7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Pyruvate kinase isoform M2 (PKM2) is a member of the pyruvate kinase (PK) family，a pivotal glycolytic enzyme that is consistently changed during tumorigenesis.PKM2 is expressed in some differentiated tissues，such as lung，fat tissue，retina，and pancreatic islets.As the rate-controlling enzyme in glycolysis，PKM2，has also been found to be expressed in embryonic，proliferating，and tumor cells，and it has been considered to be crucial for the metabolism and growth of tumor cells.Recent studies have shown that PKM2 promotes cell proliferation and suppresses cell apoptosis in various tumors.In addition，it has been reported that the PKM2 knockdown affects the Akt and ERK protein kinases.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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