Recombinant Human S100A16,BR

产品属性 Product Attributes

基本信息

别名： Protein S100-A16;Aging-associated gene 13 protein;Protein S100-F;S100 calcium-binding protein A16;S100A16;S100F;AAG13
中文名称: Recombinant Human S100A16
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 500mM NaCl, pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-handmotifs.S100 proteins are cell-and tissue-specific and are involved in many intra-and extracellular processes hrough interacting with specific target proteins.S100A16 expression was found to be astrocyte-specific.The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation.The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and insolution，resulting in good agreement between the structures with the exception of two loop regions.The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form.Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppress or protein p53，also a known inhibitor of adipogenesis.Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsivegenes，respectively.S100A16 protein is a novel adipogenesis-promoting factor.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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