Recombinant Human LILRB2/CD85d/ILT4/Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2/Lir-2/LIR2/MIR10,BR

产品属性 Product Attributes

基本信息

别名： Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2;LIR-2;Leukocyte Immunoglobulin-Like Receptor 2;CD85 Antigen-Like Family Member D;Immunoglobulin-Like Transcript 4;ILT-4;Monocyte/Macrophage Immunoglobulin-Like Receptor 10;MIR-10;CD85d;LILRB2;ILT4;LIR2;MIR10
中文名称: Recombinant Human LILRB2/CD85d/ILT4/Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2/Lir-2/LIR2/MIR10
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR).Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein.LIR-2 is expressed primarily on monocytes and dendritic cells (DC).Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence，a 440 aa extracellular domain (ECD)，a 21 aa transmenbrane segment，and a 116 aa cytoplasmic domain.LIR-2 binds to Classical MHCI proteins.Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs，a requirement for association with SHP-1.LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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