Recombinant Mouse Fc gamma RI/CD64/FCGR1A,BR

产品属性 Product Attributes

基本信息

别名： High affinity immunoglobulin gamma Fc receptor I;IgG Fc receptor I;Fc-gamma RI;FcRI;CD64
中文名称: Recombinant Mouse Fc gamma RI/CD64/FCGR1A
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD64，also known as Fc-gamma receptor 1 (FcγRI)，is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity.After binding IgG，CD64 interacts with an accessory chain known as the common γ chain (γ chain)，which possesses an ITAM motif that is necessary for triggering cellular activation.CD64 is composed of a signal peptide，three extracellular immunoglobulin domains of the C2-type used to bind antibody，a hydrophobic transmembrane domain，and a short cytoplasmic tail.CD64 mediates endocytosis，phagocytosis，antibody-dependent cellular cytotoxicity，cytokine release，and superoxide production.It is normally expressed on the surfaces of monocytes and macrophages.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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