Recombinant Mouse CD47/IAP/Leukocyte Surface Antigen CD47,BR

产品属性 Product Attributes

基本信息

别名： Leukocyte Surface Antigen CD47;Antigenic Surface Determinant Protein OA3;Integrin-Associated Protein;IAP;Protein MER6;CD47;MER6
中文名称: Recombinant Mouse CD47/IAP/Leukocyte Surface Antigen CD47
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD47，also known as Integrin-Associated Protein (IAP) and OA3，is a glycosylated atypical member of the immunoglobulin superfamily.Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig-like domain，five membrane-spanning regions with short intervening loops，and C-terminal cytoplasmic tail.CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets，and in the modulation of integrins.It plays an important role in memory formation and synaptic plasticity in the hippocampus.As a receptor for SIRPA，it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.Interaction with SIRPG mediates cellcell adhesion，it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.It may play a role in membrane transport and/or integrin dependent signal transduction.It also prevents premature elimination of red blood cells.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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