Recombinant Human LILRA5/CD85f,BR

产品属性 Product Attributes

基本信息

别名： Leukocyte immunoglobulin-like receptor subfamily A member 5;CD85 antigen-like family member F;Immunoglobulin-like transcript 11;ILT-11;Leukocyte immunoglobulin-like receptor 9;LIR-9;CD85f;LILRA5;LILRB7
中文名称: Recombinant Human LILRA5/CD85f
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5（LILRA5）is a member of the leukocyte immunoglobulin-like receptors (LILR)，comprise a family of activating and inhibitory type immunoreceptors.LILRA5 consists of a 227 amino acid (aa) extracellular domain (ECD)，a 21 aa transmembrane segment，and a 10 aa cytoplasmic tail.The ECD contains two Ig-like domains and the transmembrane segment contains a positively charged aspartic acid residue which may mediate its association with the signaling molecule，FcR common gamma chain.LILRA5 is expressed by monocytes，macrophages，and neutrophils.Cross-linking of LILRA5 on monocytes induces the expression of pro-inflammatory cytokines (IL-1beta，IL-6，TNF-alpha) as well as the anti-inflammatory IL-10.It can be detected in tissues of the hematopoietic system，including bone marrow，spleen，lymph node and peripheral leukocytes.Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines，which suggests the roles of this protein in triggering innate immune responses.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。