Recombinant Human CRTAM/CD355/Cytotoxic and regulatory T-cell molecule,BR

产品属性 Product Attributes

基本信息

别名： Cytotoxic and Regulatory T-Cell Molecule;Class-I MHC-Restricted T-Cell-Associated Molecule;CD355;CRTAM
中文名称: Recombinant Human CRTAM/CD355/Cytotoxic and regulatory T-cell molecule
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells.CRTAM is found in spleen，thymus，small intestine，peripheral blood，and it is highly expressed by Purkinje cells of the cerebellum.CRTAM is a type I transmembrane glycoprotein containing one Ig-like C2-type domain and one Ig-like V-type domain in its extracellular domain，while its cytoplasmic region shows a potential class I PDZ domain.CRTAM is expressed as a homodimer on the cell surface but does not show homotypic binding in trans.The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions.IGSF4 and T cell receptor coengagement of CD8+ cells expressiong CRTAM induces increased IFNγ or IL-22 production.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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