Recombinant Human IFN-alpha/beta R1/IFNAR1/Interferon alpha/beta receptor 1/,BR

产品属性 Product Attributes

基本信息

别名： Interferon Alpha/Beta Receptor 1;IFN-R-1;IFN-Alpha/Beta Receptor 1;Cytokine Receptor Class-II Member 1;Cytokine Receptor Family 2 Member 1;CRF2-1;Type I Interferon Receptor 1;IFNAR1;IFNAR
中文名称: Recombinant Human IFN-alpha/beta R1/IFNAR1/Interferon alpha/beta receptor 1/
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： The Interferon-α/β Receptor 1 (IFN-α/β R1) is a receptor which binds Type I Interferons including Interferon-α and -β.It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2.IFN-α/β R1，in association with IFN-α/β R2，is required for propagating antiviral signal transduction triggered by IFN-α and IFN-β.IFN-α/β R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN-α/β R2.Ligands associate with IFN-α/β R2，and this complex subsequently forms a stable ternary assembly with IFN-α/β R1.IFN-α/β R1 also associates with IFN-γ R2 even in the absence of IFN-γ stimulation.Human IFN-α/β R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand.Interferon stimulation results in an immunologic response that is especially associated with viruses.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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