Recombinant Human VEGF R1/Flt-1/FLT1,BR

产品属性 Product Attributes

基本信息

别名： Vascular endothelial growth factor receptor 1;VEGFR-1;Fms-like tyrosine kinase 1;FLT-1;Tyrosine-protein kinase FRT;Tyrosine-protein kinase receptor FLT;Vascular permeability factor receptor
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Human Vascular endothelial growth factor receptor 1(VEGFR-1，FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily.VEGFR-1 is widely expressed in human tissues including normal lung，placenta，liver，kidney，heart and brain tissues.It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes.VEGFR-1 contains seven Ig-like C2-type domains and one protein kinase domain.VEGFR-1is an essential receptor tyrosine kinase and plays an important role in theregulation of VEGF family-mediated vasculogenesis，angiogenesis，and lymphangiogenesis.It is also mediators of neurotrophic activity and regulators of hematopoietic development.VEGFR-1 is a receptor for VEGF，VEGFB and PGF.It has a tyrosine-protein kinase activity.Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA，VEGFB and PGF.It may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation，survival and angiogenesis in adulthood.Its function in promoting cell proliferation seems to be cell-type specific.VEGFR-1 can also promote PGF-mediated proliferation of endothelial cells，proliferation of some types of cancer cells，but does not promote proliferation of normal fibroblasts (in vitro).
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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