Recombinant Human Delta-like 1/DLL1,BR

产品属性 Product Attributes

基本信息

别名： Delta-like protein 1;Drosophila Delta homolog 1;Delta1;H-Delta-1;DLL1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Hepes, 150mM NaCl, 1mM EDTA, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Delta-like protein 1 (DLL1) is a type I transmembrane protein that belongs to the Delta/Serrate/Lag2 (DSL) family of Notch ligands.Mature human DLL1 consists of a 528 amino acid (aa) extracellular domain (ECD) with one DSL domain and eight EGF-like repeats，a 23 aa transmembrane segment，and a 155 aa cytoplasmic domain.Within the ECD，human DLL1 shares 91% aa sequence identity with mouse and rat DLL1.The residual membranebound portion of DLL1 can be cleave by presenilin-dependent γ-secretase，enabling the cytoplasmic domain to migrate to the nucleus.DLL1 localizes to adherens junctions on neuronal processes through its association with the scaffolding protein MAGI1.DLL1 is widely expressed，and it plays an important role in embryonic somite formation，cochlear hair cell differentiation，plus B and T lymphocyte differentiation.The upregulation of DLL1 in arterial endothelial cells following injury or angiogenic stimulation is central to postnatal arteriogenesis.DLL1 is also overexpressed in cervical carcinoma and glioma and contributes to tumor progression.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。