Recombinant Human sCD4/T-cell surface glycoprotein CD4,BR

产品属性 Product Attributes

基本信息

别名： T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;Scd4
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,1mM EDTA,PH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD4 is an approximately 55 kDa type-I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T-lymphocytes.It is a standard phenotype marker for the identification of T-cell populations.Mature human CD4 consists of a 371 amino acid extracellular region containing four immunoglobulin-like domains，a 22 aa transmembrane segment，and a 40 aa cytoplasmic domain.CD4 is expressed along with CD8 on double positive T-cells during their development in the thymus.CD4 binds directly to MHC class-II molecules on antigen presenting cells (10).This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction.CD4 also functions as a chemotactic receptor for IL-16 and，in human，as a co-receptor for the gp120 surface glycoprotein of HIV-1.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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