Recombinant Human Renin/Angiotensinogenase/angiotensin-forming enzyme,BR

产品属性 Product Attributes

基本信息

别名： Renin;Angiotensinogenase;REN
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Renin is a member of the aspartyl proteinase family produced largely in part by the juxtaglomerular cells in the kidney.Renin is produced as prorenin with 43 pro residues at the N-terminal of mature Renin.The inactive prorenin becomes activated proteolytically by trypsin，cathepsin B，or other proteinases.Renin also has a very high selectivity for substrates due to a long peptide recognition on either side of the peptide bond undergoing cleavage.An octapeptide substrate was the minimum length to be cleaved by Renin.Renin plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen，which is the only known physiological substrate of Renin.Renin releases the decapeptide angiotensin I，which in turn is further converted to vasoactive hormone angiotensin II by angiotensin converting enzyme (ACE).
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。