Recombinant Human LAG-3/CD223/Lymphocyte activation gene 3 Protein,BR

产品属性 Product Attributes

基本信息

别名： Lymphocyte activation gene 3 protein;LAG3;LAG-3;Protein FDC;CD223
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily.LAG3 contains 4 extracellular Ig-like domains.The LAG3 gene contains 8 exons.LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens.It is selectively expressed in activated T and NK cells.LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation.As a soluble molecule，LAG3 activates antigen-presenting cells through MHC class II signaling.It can lead to increased antigen-specific T-cell responses in vivo.LAG-3 has higher affinity to MHC class II than CD4.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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