Recombinant Human MICA/MHC-I related sequence A,BR

产品属性 Product Attributes

基本信息

别名： MHC Class I Polypeptide-Related Sequence A;MIC-A;MICA;PERB11.1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥85% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： MHC class I polypeptide-related sequence A，also known as MIC-A，PERB11.1 and MICA，is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily.MICA contains one Ig-like C1-type domain and is expressed on the cell surface，although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin.It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells，NKT cells，and most of the subtypes of T cells.MICA is the ligand for NK cell activating receptor KLRK1/NKG2D.MICA seems to have no role in antigen presentation.MICA leads to cell lysis by binding to KLRK1.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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