Recombinant Human Ephrin A Receptor 1/EphA1,BR

产品属性 Product Attributes

基本信息

别名： Ephrin type-A receptor 1;hEpha1;EPH tyrosine kinase;EPH tyrosine kinase 1;Erythropoietin-producing hepatoma receptor;Tyrosine-protein kinase receptor EPH;EPHA1;EPH;EPHT;EPHT1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Ephrin type-A receptor 1/EphA1 is a glycosylated member of the Eph family of transmembrane receptor tyrosine kinases.The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.The A and B classes of Eph proteins are distinguished by Ephrin ligand binding preference but have a common structural organization.Eph-Ephrin interactions are widely involved in the regulation of cell migration，tissue morphogenesis，and cancer progression.EphA1 can form pH sensitive cishomodimers on the cell surface.Membrane-bound or clustered Ephrin ligands interact with EphA1 and activate its kinase domain which is capable of Ser，Thr，and Tyr phosphorylation.Reverse signaling is propagated through the Ephrin ligand.EphA1 is widely expressed in differentiated epithelial cells，particularly in bone marrow，spleen，thymus，and testes.EphA1 is upregulated or downregulated in a variety of human carcinomas and is implicated in tumor invasiveness.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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